Bioprospecting for HIV-1 latency reversing agent (prostratin) from indigenous medicinal plants for latency reversal in HIV-1 subtypes A and D in Uganda (HIV-1_AD_LRA study)-PHASE-3
Joseph Francis Hokello
Project Summary
This Phase-3 study builds on earlier work to test the efficacy of PROVIRID, a herbal prototype derived from indigenous medicinal plants, in reversing HIV latency in subtypes A and D prevalent in Uganda. Using ex-vivo CD4+ T cells from HIV patients, the study will determine efficacy, profile phytochemicals, and publish findings. The project strengthens collaborations, builds research capacity, and contributes to Uganda’s Vision 2040 by advancing towards an HIV cure and promoting universal health.
